PubMedCrossRef 13. Jungblut PR, Muller EC, Mattow J, Kaufmann SH: Proteomics reveals open reading frames in Mycobacterium tuberculosis H37Rv not predicted by genomics. Infect Immun 2001, 69: 5905–5907.PubMedCrossRef 14. Camacho LR, Ensergueix D, Perez E, Gicquel B, Guilhot C: Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis. Mol Microbiol 1999, 34: 257–267.PubMedCrossRef 15. Russell RB, Eggleston DS: New roles for structure R788 concentration in biology and drug discovery. Nat Struct Biol 2000,

7 (Suppl) : 928–930.PubMedCrossRef 16. Daffe M, Etienne G: The capsule of Mycobacterium tuberculosis and its implications for pathogenicity. Tuber Lung Dis 1999, 79: 153–169.PubMedCrossRef 17. Zuber B, Chami M, Houssin C, Dubochet J, Griffiths G, Daffe M: Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state. J Bacteriol 2008, 190: 5672–5680.PubMedCrossRef 18. Hoffmann C, Leis A, Niederweis M, Plitzko JM, Engelhardt H: Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure. Proc Natl Acad Sci USA 2008, 105: 3963–3967.PubMedCrossRef 19. Velayati AA, Farnia P, Ibrahim TA, Haroun RZ, Kuan HO, Ghanavi J, Farnia P, Kabarei AN, Tabarsi P, Omar AR, Varahram M, Masjedi MR: Differences in Cell Wall Thickness between selleck Resistant

and Nonresistant PIK3C2G Strains of Mycobacterium tuberculosis : Using Transmission Electron Microscopy.

Chemotherapy 2009, 55: 303–307.PubMedCrossRef 20. Bordier C: Phase separation of integral membrane proteins in Triton X-114 solution. J Biol Chem 1981, 256: 1604–1607.PubMed 21. Malen H, Berven FS, Softeland T, Arntzen MO, D’Santos CS, De Souza GA, Wiker HG: Membrane and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies. Proteomics 2008, 8: 1859–1870.PubMedCrossRef 22. Olsen JV, de Godoy LM, Li G, Macek B, Mortensen P, Pesch R, Makarov A, Lange O, Horning S, Mann M: Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap. Mol Cell Proteomics 2005, 4: 2010–2021.PubMedCrossRef 23. Cox J, Mann M: MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol 2008, 26: 1367–1372.PubMedCrossRef 24. De Souza GA, Arntzen MO, Wiker HG: MSMSpdbb: providing protein databases of closely related organisms to improve proteomic characterization of prokaryotic microbes. Bioinformatics 2010, 26: 698–699.PubMedCrossRef 25. Peng J, Elias JE, Thoreen CC, Licklider LJ, Gygi SP: Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome. J Proteome Res 2003, 2: 43–50.PubMedCrossRef 26.