Ninety-six percent of patients with epilepsy aged between 20 and

Ninety-six percent of patients with epilepsy aged between 20 and 60 drank alcoholic beverages. However, in only 25 (13.9%) patients with epilepsy was the epilepsy related to alcohol; most patients (80.6%) had no definite causes. There were no local health workers who received any formal training on epilepsy before, nor did the local health agencies provide any conventional antiepileptic drugs.

Conclusion: The prevalence rates of epilepsy in the towns of Shang Zayul and Xis Zayul of the Tibet Autonomous Region were relatively Copanlisib higher

than in other areas. The alcohol-related health problems cannot be ignored. This serious situation and the large treatment gap indicate a pressing need for medical, financial and social support in this population. (C) 2010 Elsevier Inc. All rights reserved.”
“Introduction and objectives: Hypertension is one of the most prevalent and poorly controlled risk factors, especially in patients with established cardiovascular disease (CVD). The aim of this study

was to describe the rate of blood pressure (BP) control and related risk factors.

Methods: Multicenter, cross-sectional and observational registry of patients with hypertension recruited from cardiology and primary care outpatient clinics. Controlled BP defined as < 140/90 mmHg.

Results: 55.4% of the 10 743 patients included had controlled BP and these had a slightly higher mean age. Patients with uncontrolled BP were more frequently male, with a higher prevalence of active smokers, obese patients, and patients with diabetes. The rate of controlled BP was similar in patients with or without CVD. Patients with uncontrolled BP had higher levels of blood glucose, total cholesterol, low density lipoproteins and uric acid. Patients with uncontrolled BP were receiving a slightly higher mean number HDAC activity assay of antihypertensive drugs compared to patients with controlled BP. Patients with CVD were more frequently receiving a renin-angiotensin-aldosterone

axis inhibitor: 83.5% vs. 73.2% (P < .01). Multivariate analysis identified obesity and current smoking as independently associated with uncontrolled BP, both in patients with or without CVD, as well as relevant differences between the two groups on other factors.

Conclusions: Regardless of the presence of CVD, 55% of hypertensive patients had controlled BP. Lifestyle and diet, especially smoking and obesity, are independently associated with lack of BP control. (C) 2011 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S. L. All rights reserved.”
“Myostatin, a transforming growth factor-beta superfamily member, has been well documented as a negative regulator of muscle growth and development. Myostatin, which has 376 amino acids, is synthesized as a precursor protein. Polymorphism of the myostatin gene in Makoei sheep was investigated by PCR and single-strand conformation polymorphism technique (SSCP). Genomic DNA of 92 sheep was isolated from whole blood.

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