Among NH patients, 56% of whom were dippers, subclinical cardiac

Among NH patients, 56% of whom were dippers, subclinical cardiac organ damage was more pronounced than in their NN counterparts. Conclusions. In uncomplicated essential hypertensives, NH is a more frequent pattern than non-dipping; NH is associated

with organ damage, independently of dipping/non-dipping status. This suggests that options aimed at restoring a blunted nocturnal BP fall may be insufficient to prevent cardiovascular complications unless night-time BP values HDAC inhibitor are fully normalized”
“Objective: The Game Dice Task (GDT) was developed to measure decision making under known risk. The aim of this study was to translate and adapt the GDT to a Brazilian population. Method: After the GDT was translated and back-translated to Brazilian Portuguese and evaluated by eight bilingual judges, 175 Brazilian adults were divided into two groups -160 healthy volunteers and 15 traumatic brain injury (TBI) patients – and had completed the GDT. Results: Differences between genders, but not age, were observed in the healthy volunteer sample. Males more frequently chose a combination of three dice while females preferred four dice. TBI patients were more impulsive than healthy volunteers; they less frequently chose a combination of three dice and made more risky decisions. Conclusion: Because of the rigorous process used

to translate and adapt the GDT and the differences observed between patients with TBI and healthy volunteers, the Brazilian GDT was considered satisfactory for research purposes.”

The objective of this study was to assess the correlations selleck chemical between the detection of stress-associated hormone/oxidative Kinesin inhibitor stress markers in umbilical cord blood (CB) and the physical condition of the mother and neonate.


CB units collected from normal vaginal deliveries were analyzed for various biochemical markers, some stress-associated hormones, such as progesterone, cortisol, adrenocorticotropic hormone (ACTH), corticotrophin releasing factor (CRF) and oxidative stress marker 8-hydroxy-deoxyguanosine

(8-OHdG), respectively.


The progesterone concentration closely correlated with Apgar score, hemoglobin, maternal smoking and insulin concentration, respectively. In particular, its concentration in the non-smoker group and Apgar score 10 points group was significantly lower in comparison to the smoker group and Apgar score 8 points group, respectively. Cortisol concentration correlated significantly with the number of parities, pre-pregnancy body mass index (BMI), and increase of neonatal weight and height per day, respectively. In particular, its concentration in deliveries of males and first babies was significantly higher in comparison to female deliveries and second babies, respectively. In addition, a significant correlation was observed between the duration between spontaneous/artificial membrane rupture time and delivery time and the ACTH concentration.

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