2002b; Bierwagen et al. 2008; McClanahan et al. 2008). Practitioners face obstacles such as cost, institutional Compound Library clinical trial inertia, limited regional and local predictions, and uncertainty (Galatowitsch et al. 2009; Lawler 2009; Mawdsley et al. 2009). For example, Inhibitor Library supplier project managers in The Nature Conservancy

(TNC) typically develop conservation strategies based on current biodiversity, current land cover and landownership maps, and threats analyses projecting out 10 years. Climate change, if considered at all, is usually regarded as an abstract threat without articulating the mechanism of impact and without following those impacts through to building appropriate strategies and actions. To address the gap in incorporating climate considerations into biodiversity conservation efforts, we worked with 20 conservation projects to apply a common process for developing climate adaptation strategies. We assumed that a coordinated effort with a number of projects would advance our thinking MK 8931 and help establish working guidelines more quickly than an individual, piecemeal approach. To our knowledge, there has been no other effort to develop adaptation strategies for a group of existing biodiversity conservation projects simultaneously and using the same general process. The effort to develop adaptation strategies for 20 conservation

projects was viewed as a learning experiment that would shed light on a number of important questions: (1) what are the key steps needed for

addressing climate change impacts in conservation strategies? (2) How does incorporating climate change alter the focus of a project (i.e., the focal ecosystems and species and project boundary)? (3) How do existing L-gulonolactone oxidase conservation strategies change when we incorporate future climate impacts? (4) How do we make consideration of climate impacts commonplace in our conservation efforts? Here we report how climate change is expected to affect ecosystems and species in the conservation projects analyzed, and discuss how conservation strategies were modified to adapt to those impacts. The ultimate goal in sharing these early results is to help make conservation projects and their associated outcomes more robust in an uncertain future as quickly as possible. Methods Conservation projects were self nominated from across TNC’s state and country conservation programs following a general call for proposals. Half of the final 20 projects were from the United States and half from other countries where TNC operates (Table 1). Final projects selected were required to have an initial conservation plan and strategies that did not adequately consider the potential impacts from climate change.